Includes bibliographies and index.

Endobiogeny is referred to as a global systems miracle to human biology that may deliver a development in clinical medicine focused on scientific principles of consistency and investigation and the humanistic ideologies of individualization of care and mitigation of suffering with minimization of harm. The relationship between different hormones and certain biomarkers is a long and entrenched fact centered on modern physiology and scientific method. It is a systems theory of biology that deliberates the endocrine system to be the true manager of the body. This book provides state of the art information relating to the theory of endobiogeny for recent clinical practice. The book opens with the integrative five-fluid circulation system in the human body. The advent of next-generation sequencing (NGS) and genome-wide association studies (GWAS) has led to the accumulation of a vast amount of disease-gene associations. In addition, high-throughput experimental studies and proteomic technologies have resulted in extensive protein interactions maps. Connecting disease-related phenotypes to their underlying molecular mechanisms and genetic constituents is crucial for a better understanding of complex human diseases. Further, it hypothesized that the modeling system of endobiogeny would demonstrate elevated values of the cortisol in ambulatory CHF patients versus controls. It also presents novel insights into gene expression regulation during meiosis revealed by translation elongation dynamics. The ability to dynamically control mRNA translation has a great impact on many intracellular processes. Whereas it is believed that translational control in eukaryotes occurs mainly at initiation, the condition-specific changes at the elongation level and their potential regulatory role remain unclear. This book gives a recent update on the milestone, progress, and challenges in developing different models for ATTR amyloidosis research. The notion of pathways enables the representation, formalization, and interpretation of biological events or series of interactions. Herein this book, we present ComPath, an ecosystem that supports curation of pathway mappings between databases and fosters the exploration of pathway knowledge through several novel visualizations.