Search the Library Catalogue
Image from Amazon.com
Image from Google Jackets
3D cell-based biosensors in drug discovery programs : microtissue engineering for high throughput screening / William Ssempa Kisaalita.
Material type:
TextLanguage: English Publication details: Boca Raton : CRC Press, 2010.Edition: 1st edDescription: xiii, 386 p. : ill. ; 20 cmISBN: - 9781420073492
- 615.19 KIS
Contents:
Summary: "This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.
Biosensors and bioassays
Target-driven drug discovery
Comparative transcriptional profiling and proteomics
Comparative structure and function
Chemical microenvironmental factors
Spatial and temporal microenvironmental factors
Material physical property and force microenvironmental factors
Proteomics as a promising tool in the search for 3D biomarkers
Readout present and near future
Ready-to-use commercial 3D plates
Challenges to adopting 3D cultures in HTS programs
Cases for 3D cultures in drug discovery
Ideal case study design
| Item type | Current library | Collection | Shelving location | Call number | Status | Barcode | |
|---|---|---|---|---|---|---|---|
Reference
|
Kalaignar Centenary Library Madurai | ENGLISH-REFERENCE BOOKS | ஆறாம் தளம் / Sixth floor | 615.19 KIS (Browse shelf(Opens below)) | Not for loan | 162242 |
Includes bibliographies and index.
Biosensors and bioassays
Target-driven drug discovery
Comparative transcriptional profiling and proteomics
Comparative structure and function
Chemical microenvironmental factors
Spatial and temporal microenvironmental factors
Material physical property and force microenvironmental factors
Proteomics as a promising tool in the search for 3D biomarkers
Readout present and near future
Ready-to-use commercial 3D plates
Challenges to adopting 3D cultures in HTS programs
Cases for 3D cultures in drug discovery
Ideal case study design
"This book is based upon cutting-edge research conducted in the authors lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information"--Provided by publisher.