Includes bibliographical references.

This book presents the reader with a range of new interventions in the field of biomedical science from expert scientists around the world. The first part of the book is devoted to topics related to tissue culture. The contributors focus especially on the place of tissue culture in drug development, and present their findings on topics including the use of in-vitro tissue models as replacements for animal models in preclinical drug tests and animal cell culture for virus isolation. The second part ranges widely across topics in science, engineering and technology. Featured topics include the fundamentals of hydrophobic interaction chromatography, animal models of angiogenesis, new work on mitochondria function in diabetes, and new perspectives on AGE/RAGE as a mediator of insulin resistance. The book is rooted in high-quality laboratory research from across the world, and each chapter is supported by a review of the current literature. It will be text of interest to students and researchers in biomedicine, and especially for those with interests in tissue cultures, drug development and diabetes.